Know more

About cookies

What is a "cookie"?

A "cookie" is a piece of information, usually small and identified by a name, which may be sent to your browser by a website you are visiting. Your web browser will store it for a period of time, and send it back to the web server each time you log on again.

Different types of cookies are placed on the sites:

  • Cookies strictly necessary for the proper functioning of the site
  • Cookies deposited by third party sites to improve the interactivity of the site, to collect statistics

Learn more about cookies and how they work

The different types of cookies used on this site

Cookies strictly necessary for the site to function

These cookies allow the main services of the site to function optimally. You can technically block them using your browser settings but your experience on the site may be degraded.

Furthermore, you have the possibility of opposing the use of audience measurement tracers strictly necessary for the functioning and current administration of the website in the cookie management window accessible via the link located in the footer of the site.

Technical cookies

Name of the cookie


Shelf life

CAS and PHP session cookies

Login credentials, session security



Saving your cookie consent choices

12 months

Audience measurement cookies (AT Internet)

Name of the cookie


Shelf life


Trace the visitor's route in order to establish visit statistics.

13 months


Store the anonymous ID of the visitor who starts the first time he visits the site

13 months


Identify the numbers (unique identifiers of a site) seen by the visitor and store the visitor's identifiers.

13 months

About the AT Internet audience measurement tool :

AT Internet's audience measurement tool Analytics is deployed on this site in order to obtain information on visitors' navigation and to improve its use.

The French data protection authority (CNIL) has granted an exemption to AT Internet's Web Analytics cookie. This tool is thus exempt from the collection of the Internet user's consent with regard to the deposit of analytics cookies. However, you can refuse the deposit of these cookies via the cookie management panel.

Good to know:

  • The data collected are not cross-checked with other processing operations
  • The deposited cookie is only used to produce anonymous statistics
  • The cookie does not allow the user's navigation on other sites to be tracked.

Third party cookies to improve the interactivity of the site

This site relies on certain services provided by third parties which allow :

  • to offer interactive content;
  • improve usability and facilitate the sharing of content on social networks;
  • view videos and animated presentations directly on our website;
  • protect form entries from robots;
  • monitor the performance of the site.

These third parties will collect and use your browsing data for their own purposes.

How to accept or reject cookies

When you start browsing an eZpublish site, the appearance of the "cookies" banner allows you to accept or refuse all the cookies we use. This banner will be displayed as long as you have not made a choice, even if you are browsing on another page of the site.

You can change your choices at any time by clicking on the "Cookie Management" link.

You can manage these cookies in your browser. Here are the procedures to follow: Firefox; Chrome; Explorer; Safari; Opera

For more information about the cookies we use, you can contact INRAE's Data Protection Officer by email at or by post at :


24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo Principal

Home page

RA1 - Characterisation of animal lines

RA1 has as its overall objective to characterise the animal lines of the different species used as experimental models of animal infectious diseases including susceptibility, definition of surrogate markers of infection and evaluation of exposure and manipulation procedures.


Experimental infection in animals has been and is still used as a proof of an organism's disease causing ability. Although many infectious agents show a significant degree of host specificity, causing disease in only a few related species, numerous animal models have now been developed that closely mimic the course of animal and human infectious diseases. These models have been developed because they offer insights into the pathogenicity of the infection and the immune response against the pathogen, and provide a convenient system for testing new diagnostic and therapeutic tools and vaccines. However, animal populations typically exhibit considerable genetic variation for resistance to infection by a selected pathogen. This genetic variability might be used through appropriate QTL or functional genomic methodology to determine genetic mechanisms of susceptibility but may also result in the failure or inconclusiveness of experimental trials.

The use of reference lines with known sanitary and genetic status increases the results’ reliability. When available, the inbred lines stability allows to cumulate data and between experiments comparisons. These advantages have been determinant for the development of mouse models of infection in Biomedical research. But the development of emergent diseases in farm animals and the study of their transmissibility to human require the development of a model of infection directly in the target host or in mice carrying human gene involved in genetic susceptibility to diseases.


Members of the platform will share animal lines, expertise, and facilities to promote research on these invaluable tools that represent animal lines with a defined sanitary status and genetic characteristics.

  • Definition of sanitary status will be done according to available regulations and using classical immunological and microbiological tools. In addition specific amplification (PCR) of pathogen nucleic acids
  • will be done as required.
  • Genetic characterization and comparisons between lines will use modern tools from the molecular genomics and particularly SNPs markers to define within line and interlines diversity.
  • Disease susceptibility of each line will be investigated through experimental infections and pathogenesis studies that will involve potential pathogens from classical and emerging diseases. In case of inbred lines, researchers will be able to cumulate available information relative to each line.

This will help to the definition of farm animals models of infection adapted to the development and validation of new diagnosis, vaccines, and therapeutics tools. Emerging pathogens to be used in this work programme will be selected by the partners involved (see RA3).

Task leaders

  • RA1.1 – Characterisation of inbred chicken lines
    Task Leader : Institute for Animal Health (United Kingdom)
  • RA1.2 – Characterisation of dd minipigs
    Task leader: Institute for Animal Health IAH United Kingdom
  • RA1.3 – Characterisation of sheep
    Task leader: Moredun Research Institute (United Kingdom)
  • RA1.4 – Characterisation of transgenic mice
    Task leader: Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (Spain)
  • RA1.5 – Characterisation of fishes
    Task Leader: Veterinærmedisinsk oppdragssenter AS (Norway)
  • RA1.6 – Euro immunological tools
    Task leader: Institute for Animal Health IAH United Kingdom